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Sonia B. Dhoot, MD
Medical Retina and Vitreoretinal Surgeon

Sonia B. Dhoot, MD

Orange County Ophthalmologist

Specializing in Medical & Surgical Retina

Dr. Sonia Dhoot is a board-certified, fellowship-trained ophthalmologist who specializes in the medical and surgical treatment of retinal and vitreous diseases. Her clinical interests include the diagnosis and treatment of macular degeneration, diabetic retinopathy, vascular occlusions, retinal detachments, macular puckers, and macular holes.

Dr. Dhoot is a native of Southern California. After high school, she attended a combined, accelerated seven-year undergraduate/medical school program at Rensselaer Polytechnic Institute and Albany Medical College in upstate New York.

She did her internship at Arrowhead Regional Medical Center. She then completed her residency in ophthalmology and two years of vitreoretinal surgery fellowship at the University of Missouri, Kansas City. In her ­final year of training, she was elected as the Chief Resident.

Dr. Dhoot is also a contributor to medical literature having authored abstracts, original papers, and book chapters. She has published in many different ophthalmic and neurologic journals and textbooks. She is a member of the American Society of Retina Specialists and the American Academy of Ophthalmology.

Dr. Dhoot lives in Irvine with her husband Jash, a cardiologist who specializes in electrophysiology. They have three young children. She enjoys spending time with her family, watching movies, and cheering for the Los Angeles Lakers.



Sonia B. Dhoot, MD Significant Research References

Vitreoretinal Fellowship
Sabates Eye Centers
University of Missouri–Kansas City, Kansas City, Missouri, 2015–2017.

Ophthalmology Residency
University of Missouri–Kansas City, Kansas City, Missouri, 2012–2015.
Chief Resident (elect), 2014–2015.

Internship in Transitional Medicine
Arrowhead Regional Medical Center, Colton, CA, 2011–2012.

Medical School
Doctorate of Medicine
Albany Medical College, Albany, New York, 2007–2011.

Undergraduate Education
7-Year Accelerated Physician-Scientist Medical Program (BS/MD)
Rensselaer Polytechnic Institute, Troy, New York
Bachelor of Science in Biology, Magna Cum Laude, 2008.

High School Education
Riverside Polytechnic High School, Riverside, CA
Class of 2004 Valedictorian.

American Board of Ophthalmology, Diplomate, Board Certified in 2016.

Medical Board of California, since 2011.

2013 – UMKC Award for Outstanding Ophthalmic Knowledge Assessment Program (OKAP) Score

2009 – Best Poster Presentation at the 6th Annual Medical Student Investigation Day, Albany Medical College

2009 – Outstanding Clinical Science Poster at Eastern-Atlantic Student Research Forum, Miami, Florida

2008 – Recipient of SIGN Annual Meeting Scholarship, American Academy of Neurology

2025–current – Consulting Physician, Abbvie

2025–current – Apellis Advisory Board

2019–current – Consulting Physician, Glaukos

2018–2019 – Alimera Sciences Advisory Board

American Society of Retina Specialists

American Academy of Ophthalmology

The Association for Research in Vision and Ophthalmology

American Society of Cataract and Refractive Surgery

American Medical Association

10/2018–present – Barranca Surgery Center, Irvine, California

10/2018–present – La Veta Surgery Center, Orange, California

10/2018–present – Saddleback Surgery Center, Laguna Hills, California

10/2018–present – Pavilion Surgery Center, Orange, California

10/2018–present – Mission Surgery Center, Mission Viejo, California

10/2018–present – St. Joseph Hospital, Orange, California

10/2018–present – Mission Hospital, Mission Viejo, California

Dhoot SB, Kunjukunju N, Sabates N. “The Role of Prophylactic Antibiotic Use in Prevention of Endophthalmitis Following Intravitreal Injection of Anti-Vascular Endothelial Growth Factor Agents: A Meta-Analysis.” Open Journal of Ophthalmology. 2013;3(2):46-49.

Brar S, Meyer D. “Diagnosis & Management of Mucoepidermoid Carcinoma of the Lacrimal Duct.” Orbit. 2011;30(1):34-6.

Brar S, Henderson D, Schenck J, Zimmerman EA. “Iron Accumulation in the Substantia Nigra of Patients with Alzheimer’s Disease and Parkinsonism.” Archives of Neurology. 2009;66(3):371-4.

Principal Investigator

2025–current – A Randomized, Controlled, Subject- and Evaluator-Masked Phase 2 Clinical Trial Comparing EC-104 Intravitreal Implant to Ozurdex for the Treatment of Diabetic Macular Edema. Eclipse Sponsored Study.

2025–current – An IZERVAY Observational Study. Astellas Sponsored Study.

2021–present – A Decentralized Epidemiological Study of the Progression of Age-Related Macular Degeneration (AMD).

2020–2023 – A Randomized, Masked, Controlled Study of Intravitreal ILUVIEN Implant as Baseline Therapy in Patients with Early Diabetic Macular Edema (DME). Alimera Sponsored Study.

Sub-Investagator

2021–2024 – Phase III, Multicentre, Double-Masked, Randomised Study of Intravitreal OPT-302 + Ranibizumab vs Ranibizumab Alone for Neovascular AMD. Ophthea Sponsored Study.

2018 – Phase III Randomized, Masked Controlled Trial of Suprachoroidal CLS-TA + Intravitreal Anti-VEGF for Retinal Vein Occlusion. Clearside Biomedical Sponsored Study.

2017–2018 – Prospective, Multi-Center Observational Study: Assessment of EyeArt as an Automated Diabetic Retinopathy Study Tool. Eyenuk Sponsored Study.

2017–2018 – Phase II Randomized, Quadruple-Masked Trial of OPT-302 + Ranibizumab for Neovascular AMD. Ophthea Sponsored Study.

2017–2018 – Phase III Randomized, Double-Masked, Multicenter Three-Arm Study Comparing RTH258 vs Aflibercept for Neovascular AMD. Alcon Sponsored Study.

2015–2018 – Phase III Randomized, Triple-Masked Controlled Trial of Abicipar Pegol (AGN-150998) for Neovascular AMD. Allergan Sponsored Study.

2015–2018 – Phase 2/3 Randomized Trial of Zimura (Anti-CS Aptamer) for Geographic Atrophy Secondary to AMD. Ophthotech Sponsored Study.

2015–2018 – Phase III Study of Squalamine Lactate Ophthalmic Solution, 0.2% for Neovascular AMD. Ohr Pharmaceutical Sponsored Study.

2014–2018 – Phase III Randomized, Double-Masked Trial of Fovista + Avastin or Eylea vs Monotherapy for Neovascular AMD. Ophthotech Sponsored Study.

2014–2018 – Phase III Randomized, Double-Masked Trial of Fovista + Lucentis vs Lucentis Monotherapy for Neovascular AMD. Ophthotech Sponsored Study.

Dhoot SB, Pierce JB, Mofatt ME, Ariss MM. Non-Accidental Trauma: Abusive Head Trauma. In “Practical Management of Pediatric Ocular Disorders and Strabismus,” Chapter 31.

2015 – Dhoot S, Cassell M, Dyer G, Poulose A. Revisiting DRVS: Timing for Surgical Intervention for Vitreous Hemorrhage. Poster Presentation – UMKC Ophthalmology Residency Graduation; Kansas City, Missouri.

2013 – Dhoot S, Guan H, Tokuhara K. Role of Subconjunctival Bevacizumab in Post-Pterygium Excision Management. Poster Presentation – ARVO Annual Meeting; Seattle, Washington.

2012 – Brar S, Guan H, Storkersen K, Tokuhara K. Role of Subconjunctival Bevacizumab in Post-Pterygium Excision Management. Poster Presentation – Arrowhead Regional Medical Center Research Day; Colton, California.

2009 – Kabra A, Brar S, Henderson D, Zimmerman E. Iron as a Potential Pathogen and Biomarker in Frontotemporal Dementia Using High-Field T2 MRI. Poster Presentations:
– Medical Student Investigation Day, Albany Medical College
– American Academy of Neurology Annual Meeting, Seattle
– Alzheimer’s Center Luncheon, Albany Medical Center
– Buffalo Neuroimaging Analysis Center.

2008 – Brar S, Zimmerman EA, Schenck J, Henderson D. Parkinsonism in Alzheimer’s Disease Associated with Iron Accumulation in the Substantia Nigra by 3T MRI. Poster Presentations:
– Albany Medical Center Luncheon
– Medical Student Investigation Day, Albany Medical College
– Buffalo Neuroimaging Analysis Center
– American Academy of Neurology Annual Meeting, Chicago.

2003 – Uppal GS, Brar S. Cervical Epidural Injection of Steroids: Are They Effective? Presented at Kerlan Jobe Orthopaedic Foundation Fellowship Research Conference; San Diego, California.

2021–present – Board of Directors, Harvard Eye Associates

2020–present – Executive Committee Member, Harvard Eye Associates

2009 – Medical School Admissions Committee for Albany Medical College

2013–2017 – Kansas City Free Eye Clinic

2012–2013 – Congressional Glaucoma Foundation

2010–2011 – Unite For Sight

2008–2011 – Carnival on the Hill

2008, 2010 – Teddy Bear Hospital Day

2008–2011 – Prescribe Books for Kids

English, Spanish, Hindi, Punjabi

Locations

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Laguna Hills
Laguna Hills
23961 Calle de la Magdalena,
Suite 300
Laguna Hills, California 92653
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San Clemente
San Clemente
665 Camino de los Mares (at Hospital Drive),
Suites 102-103,
San Clemente, California 92673
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Orange
Orange
1010 W. La Veta Ave.,
Suite 175,
Orange, California 92868
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