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Current Clinical Research Studies

Diabetic Macular Edema (DME)

Sponsor: Eclipse Life Sciences, Inc

Randomized, Subject- and Evaluator-Masked, Phase 2 Clinical Trial Comparing EC-104 Intravitreal Implant to Ozurdex

Purpose:

To assess the safety and efficacy of EC-104 in patients with DME and prior suboptimal clinical response to IVT anti-VEGF therapy.

Eligibility info:

Diagnosed with Diabetic Macular Edema
No active proliferative diabetic retinopathy
Best-corrected vision greater than 20/400 in both eyes
A1C under 10
No diagnosis of glaucoma
No history of clinically significant rise in intraocular pressure in response to corticosteroid therapy

Participants will:

Be compensated for study visits

Investigators:

Principal Investigator: Sonia B. Dhoot, MD
Sub-investigator: Brian T. Kim, MD

Neurotrophic Keratopathy

Sponsor: ReGen Tree, LLC

Assess the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of Neurotrophic Keratopathy (Neurotrophic Keratitis)

Purpose:

To assess the effectiveness of the (RGN-259) Thymosin Beta 4 eye drops solution in the clearing of a persistent epithelial defect in patients with Neurotrophic Keratopathy.
To assess the safety of RGN-259 Ophthalmic Solution compared to placebo for the treatment of Neurotrophic Keratopathy.

Eligibility info:

Persistent Epithelial Defect (PED) that has not resolved after 1 week of conventional, non-surgical treatment
Diagnosis of Stage 2 or 3 Neurotrophic Keratopathy (Neurotrophic Keratitis)

[Participants will info]:

Be compensated for study visits

Investigators:

John A. Hovanesian, MD
Ashraf F. Ahmad, MD
Behnaz Rouhani, MD

Sponsor: University of Pittsburg

CLARIFYING THE OPTIMAL APPLICATION OF SLT THERAPY (COAST)

Purpose:

Part 1: To compare the efficacy and safety of standard vs. low energy SLT in OHT or mild-moderate OAG.
Part 2: To determine the optimal interval and energy for repeat SLT (PRN at initial assignment vs. annually at low energy).

Eligibility:

Newly diagnosed with ocular hypertension, mild, or moderate primary open-angle glaucoma
No more than 6 months of IOP-lowering eye drops within 5 years and no prior IOP-lowering lasers or surgical procedures
Best-corrected vision 20/200 in both eyes

Participants will:

Be compensated for study visit

Principal Investigator:

Ye Elaine Wang, MD

Sponsor: CLOVER Therapeutics

A decentralized epidemiological study of the progression of Age-related Macular Degeneration (AMD)

Purpose:

This is an epidemiologic study to identify genetic variants that slow down or prevent the clinical progression of intermediate AMD through advanced AMD.

Eligibility:

Current patients (been seeing our providers for at least the past 3 years) diagnosed with intermediate or advanced AMD

Principal Investigator:

Sonia B. Dhoot, MD

Sub-Investigator:

Brian Kim, MD

FAQS

What is a clinical trial?

A clinical trial is a research study focused on evaluating the safety and efficacy of new medical treatments. Treatments can include new medical drugs, new combinations of drugs, new medical devices or surgical procedures, or new medical approaches.

Why should I participate in a clinical trial?

Participating in clinical trials is important in contributing to improving and developing new medical treatments for the future. Additionally, the studies can help progress science and overall improve the health and wellbeing of others. Participants in the studies not only aid others, but may also receive the newest treatments before the general public.

Which trial can I participate in?

Your doctor can help determine which clinical trial is right for you. They may refer you to a clinical research coordinator who can offer more information about the research studies that are available and suitable for your conditions.

Is there a cost to participate in a study?

There is no cost to participate in a clinical research study. As a research study participant, you may be eligible to receive a new treatment drug or device for free as well as compensation for your time in the study.

Currently Recruiting for Clinical Research Studies

Current Clinical Research Studies

Diabetic Macular Edema (DME)

Neurotrophic Keratopathy

FAQS

What is a clinical trial?

Why should I participate in a clinical trial?

Which trial can I participate in?

Is there a cost to participate in a study?

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